On the Dynamical Approach of Quantitative Radiation Biology
نویسنده
چکیده
A quantitative approach in radiation biology based on the clonogenic method and cell survival curves in various conditions are introduced. The cell survival curves seem to have universality with regard to its functional form; in other words, functional form of survival curve seems to be unchanged under various conditions including different species. Various factors affecting the radiosensitivity have been introduced to find macroscopic nature of living organisms. Mathematical models that describe cell sur‐ vival curves have been presented for discussing the derivation of the mathematical form based on biological mechanism. Finally, the possibility that the structural change of chromosome affects the repair process is discussed.
منابع مشابه
Dynamical distance as a semi-metric on nuclear conguration space
In this paper, we introduce the concept of dynamical distance on a nuclear conguration space. We partition the nuclear conguration space into disjoint classes. This classification coincides with the classical partitioning of molecular systems via the concept of conjugacy of dynamical systems. It gives a quantitative criterion to distinguish dierent molecular structures.
متن کاملHuman 3-D tissue models in radiation biology: current status and future perspectives
In this review, we discuss the use of a variety of 3-D models (particularly 3-D skin, lung, breast and endothelial) in radiobiological research and highlight the differences in responses compared to 2-D culturing conditions (monolayers). We review the characteristics of existing 3-D models and aim to point out the substantial advantages 3-D cultures provide for modern radiobiology. In particula...
متن کاملA Dynamical System Approach to Research in Second Language Acquisition
Epistemologically speaking, second language acquisition research (SLAR) might be reconsidered from a complex dynamical system view with interconnected aspects in the ecosystem of language acquisition. The present paper attempts to introduce the tenets of complex system theory and its application in SLAR. It has been suggested that the present dominant traditions in language acquisition research...
متن کاملمکانیسم تولید و ویژگیهای تابش پرتوی ایکس پارامتری حاصل از الکترونهای نسبیتی در یک بلور
In this paper, the parametric X-ray radiation (PXR) spectral-angular distribution in the framework of the dynamical and kinematical diffraction theory was investigated in details. It is shown that dynamical diffraction effects can be increase with intensity of radiation, increase threshold energy saturation and the change in polarization of the radiation. Therefore, some unique properties of P...
متن کاملQuantitation of genome damage and transcriptional profile of DNA damage response genes in human peripheral blood mononuclear cells exposed in vitro to low doses of neutron radiation
Background: Humans are exposed to ionizing radiation from different sources that include natural, occupational, medical, accidental exposures. Evaluation of the effect of low level of neutron exposure to human cells in vitro has important implications to human health. Attempts were made to measure genome damage, transcriptional profile of DNA damage response and repair genes in peripheral blood...
متن کامل